Adler worked on energy policy matters in Washington, DC, and practiced estate planning law for UHNWI and philanthropists with the Weidenfeld Law Firm. In parallel to that work, he had a long career as a catalytic leader in diverse contexts, building a group of companies that developed low pollution automotive technology (Positive Transportation), co-founding a company that developed low pollution cleaning technology (Global OIG), and co-founding the first synthetic biology venture fund (Bioeconomy Capital), among other activities. Highlights of his career include co-producing a documentary film with PBS (with music by Radiohead), and delivering the keynote address to the annual meeting of the 2020 Family Office Association. He continues to manage a number of special purpose investment vehicles (administered by Eisner Amper), serve as trustee of a number of trusts, and fulfill a variety of philanthropic roles.